Wagner Genetics Series Spring 2008

Big Cats, Little Cats, and Their Genes

Professor Mary Beth Davis
medavis@brynmawr.edu

   Domestic cats are the revered and treasured pet-companions of people throughout the world. These cats, however, retain the predatory nature, grandeur, and mystique of their wild feline relatives. The course will begin with the recent DNA studies that elucidated evolutionary relationships between cat species. Most of the course will focus on understanding the genetic basis of specific traits in the domestic cat.

Course Syllabus:

Wednesday, January 16, 2008: Big cats and little cats: introduction to the family Felidae
An overview of the classification of the more than 35 cat species from the big cats of the African savanna to the worldwide domestic cat.

Wednesday January 23, 2008: Evolution of the cat family
Recent DNA studies of 37 living cat species have provided insights into the evolutionary history, world migrations, and development of these species.

Wednesday January 30, 2008: The diversity of cat breeds
Approximately 40 cat breeds are recognized by “cat fancier” groups. The class will examine the development of cat breeds and the history of cat fancier organizations.

Wednesday February 6, 2008: Coat colors, calicos, and tortoise shells
The lecture will explore a few of the complex cellular, genetic, and biochemical processes that determine coat color and patterns of color in domestic cats.

Wednesday February 13, 2008: Morphology: No tail, extra toes, and folded ears
Classical genetics studies have identified the patterns of inheritance for many cat traits. Some interesting traits that affect cat body structure will be discussed.

Wednesday February 20, 2008: Why don’t cats like sweets?
Cats often seem indifferent to sugary foods. Analyses of genes involved in taste sensation show that cats lack the receptor for sweetness. The lecture will cover the sensory process of taste and the specific defect in the cat’s sweet taste receptor gene.

Wednesday, February 27, 2008: Cat genetic profiling and forensic science
DNA markers have been used to create a population genetic profile and forensic database for domestic cats. In a 1990’s court case the forensic analysis of car hair from a crime scene was used as prosecutorial evidence. The court case and the development of the cat DNA database will be discussed.

Online Resources

A. Cat genetics
The Domestic Cat (Felis Catus) Genome Project - Web site for the NIH research effort focused on sequencing the genome of the domestic cat
Feline genetics for the general public
Genetics of coat color in domestic cats - An indepth reference on the genes involved in conferring coat colors in cats and their mechanisms of action

B. Resource pages about "big cats"
BigCats.com- "News, editorials, pictures, and information about all big cats and wild cats."

C. Cat Evolution
Saber Tooth Tiger Information from the University of California Museum of Paleontology

D. Cat Breeds
Cat Fanciers Association, Inc. - "the world's largest registry of pedigreed cats"
About Cat Breeds - Section of a web site with basic information about cats and many links to other reference sites on specific topics about cat breeds

E. Conservation and preservation groups for Big Cat species
The Clouded Leopard Leopard Project
Feline Conservation Federation - "The FCF is comprised of a wide range of exotic cat enthusiasts such as professional breeders and educators, sanctuary and zoo owners and individual "pet" owners."

F. Miscellaneous Websites
Cats with Polydactyly - general information and photos of cats with extra toes
Scottish Fold breed - information about the history of the Scottish Fold breed from the Cat Fanciers Association, Inc. web site
Annotated collection of web links for sites about felines - sponsored by the Veterinary Support Personnel Network


Return to the homepage for the Genetics Series at the Wagner Free Institute of Science

Latest update: January 22, 2008
Questions? Email Mary Beth Davis.